Searchable abstracts of presentations at key conferences on reproductive biology and medicine

ra0001p285 | (1) | WCRB2014

Distinct sex-specific gene expression changes in the human placenta in association with childhood allergy at 2 years

Tuck Astrud , Osei-Kumah Annette , Saif Zarqa , Clifton Vicki L

The prevalence of childhood allergic disease has increased dramatically in developed countries. Modern environmental changes are hypothesised to be causing deviations in fetal programming, in which the placenta plays a central role, increasing the prevalence of disease. We hypothesised that susceptibility to childhood allergy is determined by changes in placental function that programs fetal immune function. In this study we aimed to identify candidate genes and pathways in hu...